WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Mayank Bansal, Manoj Kumar Gupta*, Rakesh Kumar Gupta, Arindam Chatterjee and Mamta Sharma

ABSTRACT

Mouth dissolving film (MDF) is a pharmaceutical dosage form that dissolves or disintegrates rapidly in the oral cavity, releasing medication for absorption through the oral mucosa (lining of the mouth) and/or for swallowing. These films are designed to be convenient for patients who may have difficulty swallowing traditional oral dosage forms like tablets or capsules. Mouth dissolving films are typically composed of water-soluble polymers that rapidly disintegrate upon contact with saliva. The film may also contain active pharmaceutical ingredients (APIs), sweeteners, flavoring agents, and other excipients. The rapid disintegration of the film in the mouth allows for quick and efficient drug delivery. The films are easy to administer, especially for individuals who have difficulty swallowing or for pediatric and geriatric patients. Since the drug is delivered directly through the oral mucosa, it can lead to a faster onset of action compared to traditional oral dosage forms that need to pass through the gastrointestinal tract. The oral mucosa provides a rich blood supply, which can lead to improved bioavailability for certain drugs. Mouth dissolving films are often more convenient and discreet than traditional dosage forms, making them suitable for on-the-go use.

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