WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Heba S. Abdul Wahaab*, Alaa G. Hussein and Ban J. Qasim

ABSTRACT

Background: salivary gland tumors comprise about 6% of head and neck neoplasms and about 0.5% of all malignancies in humans. Most SGTs are located in major salivary glands approximately 80% in the parotid gland, and are rare in the sublingual glands <1%, majority of tumors arising from submandibular, sublingual and minor salivary glands are malignant. Objective: The aim of this study is to assess pathological types of major salivary glands tumors and their clinical correlation in a sample of Iraqi patients. Methods: A retrospective study including analysis of 100 randomly selected cases with major salivary gland tumors collected from Al-Emamain Al-Kadhmain Medical city and Bagdad medical city from October 2017 to January 2023. Results: In this study Mean age of patients was 44.19 +15.72 years, (41-60y years) was the most common age group for developing salivary gland tumors. Male patients were predominant 65% and female 35% with male to female ratio 1.8:1. Malignant tumors were accounted 39% while benign tumors were 61%. As for histological types, pleomorphic adenoma was the most common benign tumor 47% followed by warthin tumor 11%, basal cell adenoma2%, myoepithelioma 2%, oncocytoma 2%, cystadenoma 2%, hemangioma 2% and lipoma 2%. Mucoepidermoid carcinoma was the most common malignant tumors 17% followed by acinic cell carcinoma 3%, squamous cell carcinoma 3%, poorly differentiated carcinoma 2%, carcinoma ex pleomorphic adenoma 2%, basal cell carcinoma 2%, adenoid cystic carcinoma 1% and metastasis (breast) 1%. However, No significant association was found between age, sex, and sit with major salivary gland tumors. There was a significant association between gross feature and nature of salivary gland lesions since most solid lesion were malignant and most cystic lesion were benign (with p value of 0.035). Conclusion: Benign tumors were more common than malignant tumors with Pleomorphic adenoma was the most common benign tumor in parotid gland followed by warthin tumor, Mucoepidermoid tumor was the most common malignant tumor follow by acinic cell carcinoma. Male patients were the most commonly diagnosed with MSGTs and parotid gland was most common site for both malignant and benign tumors. Most common age group (41-60 years). According to clinicopathological features, Gross features of the lesions were the most significantly associated with the nature of major salivary gland tumors.

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