WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Yolande Dogore Digbeu*, Siaka Binaté, Souleymane Traoré, Edmond Ahipo Dué, Brou Kouakou and Gnakri Dago

ABSTRACT

The aim of this study was to find out the in vivo impact of yam composite flours made by Digbeu et al.[1] usage as potential weaning diets and show the relationship between blood levels of urea and creatinine with blood glucose levels, cholesterol and triglycerides in young experimental wistar albino growing rats. Potential weaning diets formulated from available plants (yam Dioscorea alata variety Bètèbètè and Dioscorea cayenensis variety Lokpa, soybean and cassava) and animal (rats wistars) sources were evaluated for their nutritional efficiency in a comparative study. A total of thirty six (36) males wistar albino rats were divided equally into 6 groups of 6 animals each, housed in stainless steel cages and fed ad-libitum on 6 different types of weaning formulae. Six different diets: RTC, RCC, FBBF, FBBNF, FLOF and FLONF were prepared and fed to weaning rats for a period of 28 days of which one group served as the control ( RTC, a commercial weaning food); one served as a reference protein (RCC) and the rest as test groups were used. The experimental design for the animal feeding trial was a single factor, Completely Randomized Design (CRD). Animal experimentation lasted 28 days among which four days of adaptation with a commercial diet of standard type. Results were recorded as values of mean± S.E unit (range of values): At the end of the experiment, the animals were anesthetized and killed, and blood was drawn immediately for analysis of the biochemical profile: total cholesterol, triglycerides, glucose, creatinine concentration and urea concentrations. Results showed a no significant disturbance of plasma biochemical parameters throughout the experiment. Therefore, the liver and the kidneys do not present dysfunction due the fact those carbohydrate metabolisms were quickly hydrolyzed.

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