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Abstract
CLINICOPATHOLOGICAL ASSESSMENT OF ASCITIC FLUID CYTOMORPHOLOGY IN A SAMPLE OF IRAQI PATIENTS
Marwa M. Ekrayyem*, Ban J. Qasim and Alaa G. Hussein
ABSTRACT
Background: the International System for Reporting Serous Fluid Cytopathology was applied to report serous effusion. Effusion cytopathologic evaluation can be challenging due to multiple, different processes affecting serous cavities, ranging from benign (infectious, autoimmune) to malignant processes (primary or metastatic neoplasms). Method: A retrospective study included the analysis of 147 randomly selected samples of ascitic fluid sent to the Teaching Laboratories of Al-Emamain Al-Kadhmain Medical City (AS) from January 2020 to January 2023. Results: In this study, Mean age of 47+_19.41 years. Females to male ration 1.5:1, Abdomenal distension was the clinical presentation for all cases. Chronic liver disease 38 (25%) was the most common associated diseases. Transudate fluid was the most common ascitic fluid appearance 90(61%), the percentage of hemorrhagic effusion 11(7%). Pleural effusion 12 (8%) was the most common radiological finding As for the international system for reporting serous fluid cytopathology 4(3%) are classified as non-diagnostic or unsatisfactory samples, 92 (63%) are negative for malignancy, 29 (20%) are atypical of undetermined significance, 15 (10%) are suspicious for malignancy, 7 (5%) are malignant, and finally, the most common diagnostic categories was negative for malignancy (ll,NFM) 63%. Conclusion: Most of cases were adult Females, Abdomenal distension and dyspnea was the most common clinical presentation, Chronic liver disease was the most frequent associated disease ,Pleural effusion was the most common radiological finding negative for malignancy (ll,NFM) was the most common diagnostic categories.
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