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Abstract
CLINICOPATHOLOGICAL ASSESSMENT OF LARYNGEAL LESIONS IN A SAMPLE OF IRAQI PATIENTS
Shaymaa A. Mohammed*, Ban J. Qasim and Alaa G. Hussein
ABSTRACT
Background: Laryngeal lesions can create lot of mental and emotional tension in the patient and the family. Earlydiagnosis of the lesions can lead to effective management and good recovery. Histologically it is divided tobenign, borderline and malignant, most common benign lesion is vocal cord nodule and most common malignantlaryngeal lesion is squamous cell carcinoma. Objective: This study aims to assess the types of laryngeal lesions ina sample of Iraqi patient in correlation with clinicopathological parameters (age, sex, smoking history, lesion site ,clinical presentation, grade of malignant lesions, pathological stage and lymph node status). Methods: Aretrospective study of 83 randomly selected patients have laryngeal lesions collected from Teaching Laboratoriesof Ghazi Al-Harriri teaching hospital, from March 2018 to January 2023. Results: Laryngeal lesions found to bemore frequent in male (78. 3%), the age group (51-60) years more than other age groups, benign lesions count(44.6%), borderline lesions (8.2%), malignant lesions (47.0%), hoarseness of voice was the common clinicalpresentation in all types of laryngeal lesions. Most patient with benign and borderline lesions were nonsmokers(63.9%) and (50%) respectively, while most patients with malignancy were smokers (65%). vocal cord nodule isthe most common benign lesions (62.6%), moderate dysplasia is the most common dysplastic changes (57.1%)and squamous cell carcinoma is the most common laryngeal cancer (97.4%). Conclusion: Vocal cord nodule is themost common benign laryngeal lesions; squamous cell carcinoma is the most common malignant laryngeal lesions.Age and smoking is the main risk factors for malignant transformation of laryngeal lesions.
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