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Abstract
RISK OF PANCREATITIS FOLLOWING BILIARY STENTING WITH OR WITHOUT ENDOSCOPIC SPHINCTEROTOMY
Said Muse Yusuf, Ping Yao and Sakarie Mustafe Hidig*
ABSTRACT
Background and Aim: Endoscopic sphincterotomy (EST) effectiveness before endoscopic biliary stenting in post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP) prevention remains unestablished. This study aimed to determine the impact of EST prior endoscopic biliary stent placement in PEP. Methods: One hundred and fifty patients of different ages with biliary stricture needing ERCP were enrolled and randomly grouped into the non-EST (n=75) and EST (n=75). The researchers followed up with the participants for one month after the ERCP procedure and collected data on PEP occurrence and adverse events. The primary measure was PEP incidence within two days after the biliary stenting. The secondary outcome measures evaluated included recurrent biliary obstruction (migration, dislocation, and occlusion), adverse events connected with EST (bleeding and perforation), cholecystitis, and cholangitis after the first transpapillary biliary drainage. Results and Conclusion: 16% of patients who had biliary stenting after EST got pancreatitis, while only 9.3% of those who had biliary stenting without EST developed pancreatitis. The risk of pancreatitis is higher in endoscopic biliary stenting patientsafter undergoing EST.
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