WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Noor Alhuda Khalid Abdalmeer Muhy and Dr. Sazan Abdulwahab Mirza Al-Atrooshi

ABSTRACT

Background: Pancreaticoduodenectomy (Whitles's technique) treats pancreatic, bile duct, duodenal, and periampullary carcinomas. About 5% of gastrointestinal cancers are ampullary and periampullary carcinomas. The research examines Whipple's specimens' tumour incidence by histological diagnosis, age, sex, and other clinicopathological variables. Method: We analyse Whipple's material histopathologically to determine these tumours' diagnosis, grade, stage, nodal status, marginal status, prognosis, and incidence. This research analyses the incidence of different tumours in Whipple's material, calculates the sex ratio, then grades and stages the tumours using the WHO grading system. And to compare incidence with other research. Methods: Histopathology data of all Whipple's resection patients from January 2019 to October 2013 were examined. We studied the slides and computed parameters. Results: Out of 100 whipple's resection cases, the age range was 26–85, with 46–65 being the most prevalent. 80 percent of sex distribution situations 54% males were affected. Most instances were grade II (40%), T2 (18%), and N0 (26%). Ampullary tumours were the most prevalent lesions at 55%. Pancreatic age, histopathological type, grade, and stage correlated significantly. Age, histopathological type, grade, and stage correlated with pancreatic adenocarcinoma in 17%, 12% grade II, and 8%T2. Among benign lesions, ampullary adenomyoma 4%, chronic pancreatitis 3%, and cholangiocarcinoma 13% were mentioned. Conclusion: In the analysis of the whipple procedure ampullary adenocarcinoma was the commonest neoplasm followed by pancreatic adenocarcinoma and cholangiocarcinoma was the commonest periampullary malignant neoplasm.

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