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COMPARISON OF THE CLINICAL EFFICACY BETWEEN ONDANSETRON AND TRAMADOL IN PREVENTING POST-ANESTHETIC SHIVERING IN CESAREAN SECTION UNDER SPINAL ANESTHESIA
Dr. Sarah Dakhil Miri*, Dr. Usama H. Al Hassani, Dr. Zainab Hashim Aziz
Background: Shivering is a cause of discomfort and dissatisfaction in patients undergoing cesarean section under spinal anesthesia. For prevention of this complication, different drugs are used. Aim of study: To evaluate the efficacy ondansetron and tramadol for prevention of intra and p o s t operative shivering in patients undergoing cesarean section with spinal anesthesia. Methods: 70 patients, ASA I, females, age between (18-38), scheduled for cesarean section under spinal anesthesia, were randomly allocated to two groups, group O (received 8mg ondansetron), and group T (received 1mg/kg tramadol) as prophylactic dose after delivery of baby. Patients were evaluated regarding their heart rate, mean arterial blood pressure, oxygen saturation, core temperature, peripheral temperature and post anesthetic shivering scale. Results: The comparison between two studied groups by hemodynamic parameters of name arterial blood pressure, heart rate, oxygen saturation, there were no significant differences in all times before and after delivery of baby and drug given. In mean of core temperature, after 5, 10, 15, 20min after giving drug and in recovery, after 30, and 60 min from recovery was significantly higher in group O than that in group T. While in mean of peripheral temperature after 10, 15, 20min after giving drug and in recovery, and 30, and 60 min after recovery swa significantly higher in group O than that in group T In mean of post- anesthetic shivering scale, there were no significant differences in all times after delivery of baby and giving drugs. Conclusion: The prophylactic administration of ondansetron (8mg) or tramadol (1mg/kg) produces significant anti-shivering effect in patients undergoing cesarean section under spinal anesthesia without any significant side effects. Ondansetron is significantly more effective than tramadol.[Full Text Article]