WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Ali Iskandar Antakli, Sahar Taher Hasan and Basel Mohammad Mohammad

ABSTRACT

Background: Polycystic Ovary Syndrome (PCOS) is a widespread endocrine disorder that affects 4-8 percent of women during reproductive age. Infertility affects 40 percent of women with (PCOS). About 90-95% of women in infertility clinics have polycystic ovarian syndrome due to lack of ovulation. Ovarian perforation by laparoscopy is the second line after medicinal treatment. Objective of the research: to evaluate the effect of Laparoscopic Ovarian Drilling on ovarian reserve in patients with polycystic ovarian syndrome before and after LOD measured by the levels of anti-Mullerian hormone in the blood (AMH), FSH hormone on a specific day from the onset of menstruation, ovarian volume and (AFC) antral follicle count. Patients and methods: This study was conducted on 60 PCOS patients resistant to clomiphene citrate therapy who underwent LOD ovarian perforation at Tishreen University Hospital. The syndrome was diagnosed on the basis of the Rotterdam criterion and ovarian diseases detected by transvaginal ultrasound were excluded from the study. Results: there was a significant negative correlation between age and the difference in the level of AMH in the blood before and after LOD. There is no statistically significant relationship between obesity or clinical hyperandrogenism (hirsutism and / or acne vulgaris) and any differences between pre-and post-LOD values of ultrasound or biochemical markers of ovarian reserve. The presence of menopause was significantly associated with a higher difference between the AFC before and after LOD of the ovaries. Anti-Mullerian hormone, AFC and ovarian size decreased significantly after LOD (P