WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

M.D. Leen Hasan*, Dr. Raja Rajab and Prof. Dr. Louai Hassan

ABSTRACT

Background and Objective: It is well-known that many women experience periodic physical and psychological symptoms during the luteal phase of the menstrual cycle. These symptoms, collectively known as premenstrual syndrome (PMS), affect approximately 20-30% of women. PMS is characterized by various physical and psychological manifestations, including palpitations, lower back pain, bloating, abdominal discomfort, headaches, fatigue, weight gain, acne, changes in appetite, insomnia or excessive sleep, emotional sensitivity, depression, anger, irritability, and mood swings. Several studies suggest that vitamin B6 might be effective in alleviating the emotional and physical symptoms associated with this syndrome. Objective: The objective of this study is to determine the effectiveness of vitamin B6 in managing the physical and psychological symptoms of premenstrual syndrome. Methods: This pilot prospective study involved 72 patients who sought treatment for premenstrual syndrome at the women's clinic in Tishreen University Hospital, Lattakia, between the years 2022 and 2023. The age range of the participants was between 18 and 45 years. Results: Following a three-month treatment regimen of daily 100 mg doses of vitamin B6, a significant reduction in the severity of both physical symptoms (P-value < 0.05) and psychological symptoms (P-value < 0.05) was observed. Additionally, there was a significant decrease in the number of symptom days (P-value < 0.001). Conclusion: Vitamin B6 has proven to be an effective treatment option for reducing the severity of physical and psychological symptoms associated with premenstrual syndrome. It is a readily available treatment with minimal side effects.

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