WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Dr. Mohammed Riyadh Khudhur*, Dr. Saif Riyadh Salih, Dr. Khaleel Younus Khalaf

ABSTRACT

Background: Heart failure (HF) is a leading cause of morbidity and mortality; in medical wards of hospital with more than 100,000 yearly admissions in the United Kingdom, it is expected to account for roughly 5% of hospitalizations. The prevalence of HF is generally 3-20 per 1000 people. According to broad consensus, HF causes hepatic dysfunction, which leads to an increase in enzymes suggestive of hepatocellular damage. Aim of the study: To determine the effect of each type of HF on ALT and AST. Patients, Materials, and Methods: A case-control study involving 118 person with Heart failure as cases and 30 apparently healthy people as controls. The research was conducted during the period from the 1st of November 2005 to the 15th of May 2006, in Ibn–Sena teaching hospital and Al-Salam general hospital; the cases were from the medical ward, emergency unit and cardiac care unit (CCU). The levels of Aminotransferases were tested for the entire study sample. Results: Among the 118 cases with HF; 66 were males and 52 were females, their mean age was 59.06 ± 10.13. BMI was 25.18 ? 3.04, current smoking found in 44.1% of them. While among the 30 controls; 16 were males and 14 were females, their mean age was 57.53 ± 5.19, the mean BMI was 25.70 ? 1.82, with 36.7% of the controls were smokers. The three types of HF showed statistically significant differences with the controls group for both ALT and AST at p