WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Reem Yousif Ali Ghalib Yassin and Dr. Nadia Hameed

ABSTRACT

Background: RCC is the most prevalent kidney cancer. It causes 90% of kidney cancers and 2% of adult cancers. The 2020 Iraqi Cancer Registry reported 200 new kidney cancer cases, 129 males and 71 females, with an occurrence rate of 2.97/100000 male population and 1.68/100000 female population. This research examined the epidemiology, histopathology, and staging of renal cell carcinoma patients at Ghazy AL-Hariri Surgical Specialty Teaching Hospital and identified characteristics related with advanced staging and grading. Method: A cross sectional study was conducted at Ghazy AL-Hariri Surgical Specialty Teaching Hospital, Medical City Health Directorate during the period from January, 2020- July 2022. All records of patients with renal cell carcinoma available during the study period were reviewed and a data collection form was prepared to collect the available data from patients’ pathological records. Results: The present research comprised 100 renal cell carcinoma cases, 65 (65%) of which were male, roughly 2:1. Their mean age was 53.4 ± 10.8 years, ranging from 30 to 80. Radical nephrectomy was done on 88.0% of right kidney tumours. Most tumours were lower pole (35.0%), conventional renal cell CA/clear cell type (76.0%), and unifocal (96.0%). 8 individuals had sarcomatoid characteristics, 38 had kidney-limited tumours, and 29 had perinephric fat infiltration. Grading showed that 49.0% of patients were G2, 24.0% G3, and 62.0% pT3. 91% had no lympho-vascular invasion and all had clear surgical margins. The tumour size ranges from 1.5-20 cm with a mean of 6.7 ± 3.3 cm SD. Patients with pT2 and pT3 had larger tumours than those with pT1 (ANOVA, P

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