WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Ghufran Bayan Abd-Ali*, Besmah Mohammed Ali and Furat Yehea Muhsin

ABSTRACT

Background: In recent years, epidemiologic and laboratory studies have implied that low vitamin D level has a role in the pathogenesis of breast cancer. studies have shown that 1, 25 (OH) vitamin D inhibits proliferation of breast cancer cells and makes them more differentiated; also, it seems to cause apoptosis. objectives: The projected study aims to assess the vitamin D level and its role in association to tumor characteristics in females with breast cancer visiting oncology clinic in Oncology teaching hospital at Baghdad medical city. Materials and Methods: Across sectional study was conducted on females with breast cancer visiting oncology clinic in Oncology teaching hospital at Baghdad medical city/Iraq. Participants from age 18 years had been included for the study and selected by a convenient sampling technique. We used a pre-tested questionnaire list, vitamin D level measurement and tumor characteristics. Results: A total of 75 female participants included in the study, the prevalence of low D3 level is 86.7% expressed some degree of deficiency ranging between deficient 44% and suboptimal 42.7%. Conclusion: In this study we found inverse association between vitamin D and breast cancer risk specially among postmenopausal women, the lacking in vitamin level more in progressing with staging and those with lymphatic involvement.

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