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Abstract
RİSK FACTORS ASSOCİATED WİTH AUTİSM SPECTRUM DİSORDERS
*Nisreen Ali, Department of Pediatric, Tishreen University, Faculty of Medicine, Lattakia, Syria
ABSTRACT
Background: Autism spectrum disorder(ASD) is one of the most prevalent neurodevelopmental disorders which can affect the health related quality of life outcomes of the affected children and their families. Objective: The aim of this study was to identify the significance of certain risk factors for autism. Materials and Methods: An Analytic Case Control study was conducted in 148 patients with autism and 148 children diagnosed with other neurological conditions aged 2-10 years. They are selected from pediatric neurology clinic, Tishreen University Hospital and Centers Specialized in caring for children with autism, Syria between June 2021 and June 2022. Result: A total of 296 children, 215 males (72.6%) and 81 females (27.4%) with mean age 5.48± 2.1 years were included in the study. The prevalence of autism was increased significantly with decreasing of gestational age (p:0.001). Parental factors that associated significantly with autism were: paternal age older than 45 years(p:0.02), presence of consanguinity(p:0.003), family history of autism(p:0.001), parents, autoimmune disease(p:0.01), and smoking during pregnancy(p:0.001). Gestational age
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