WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
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Abstract

RİSK FACTORS ASSOCİATED WİTH AUTİSM SPECTRUM DİSORDERS

*Nisreen Ali, Department of Pediatric, Tishreen University, Faculty of Medicine, Lattakia, Syria

ABSTRACT

Background: Autism spectrum disorder(ASD) is one of the most prevalent neurodevelopmental disorders which can affect the health related quality of life outcomes of the affected children and their families. Objective: The aim of this study was to identify the significance of certain risk factors for autism. Materials and Methods: An Analytic Case Control study was conducted in 148 patients with autism and 148 children diagnosed with other neurological conditions aged 2-10 years. They are selected from pediatric neurology clinic, Tishreen University Hospital and Centers Specialized in caring for children with autism, Syria between June 2021 and June 2022. Result: A total of 296 children, 215 males (72.6%) and 81 females (27.4%) with mean age 5.48± 2.1 years were included in the study. The prevalence of autism was increased significantly with decreasing of gestational age (p:0.001). Parental factors that associated significantly with autism were: paternal age older than 45 years(p:0.02), presence of consanguinity(p:0.003), family history of autism(p:0.001), parents, autoimmune disease(p:0.01), and smoking during pregnancy(p:0.001). Gestational age

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