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Abstract
CORRELATION OF VITAMIN D LEVEL WITH THE TYPE 2 DIABETES MELLITUS IN MOSUL CITY
*Dr. Atlallah Hassan Hilal and Dr. Mohammad Ahmed Zanhar
ABSTRACT
Background: Vitamin D insufficiency and type 2 diabetes mellitus (T2DM) and the metabolic syndrome have been linked by epidemiological studies. It is unknown whether this association results from causation or confounding. Aim of the study: To examine the relationships between baselines vitamin D levels in Diabetic patients in Mosul and to compare its level between the controlled T2DM and the uncontrolled. Patients and Methods: In this hospital based cross-sectional study, the data were collected through direct interview with the patients. The diabetic patients were chosen and 143 patients were collected by a simple randomization technique at Mosul General Hospital during the period from 1st of October to 31st of December 2022. The data were collected by questionnaire form that includes sociodemographic characteristics as age, sex, occupations. Anthropometric measurements were calculated. The patients were sending for blood investigations that involved glucose level, HbA1c, and vitamin D level. Results: The mean age of the study sample was 52.4±5.12 years and male to female ratio equal to 1:0.6. The mean level of the FBS among the current study sample was 234.51± 21.38 mg/dl, HbA1c was 7.92±1.94, and vitamin D was 19.25±2.96 ng/mL. According to educational levels and control status, 60.9% of uncontrolled DM and 33.9% of controlled DM among low educational level had low vitamin D level while 39.1% and 66.1% of uncontrolled and controlled DM with high education had low vitamin D level; the difference was statistically significant (p=0.002). The mean of vitamin D (Vitamin D insufficiency) among the uncontrolled DM (21.56±4.35) ng/mL was lower than that of the controlled DM (26.82±1.67) ng/mL in a statistically significant way (0.001). Moreover, the mean of vitamin D in the deficiency status among the uncontrolled DM (12.54±3.62) ng/mL was significantly (p=0.000) lower than that among the controlled DM (18.32±2.11) ng/mL. Correlation of vitamin D level with HbA1c showed an inverse good correlation coefficient (r= -0.856) which was statistically significant (p=0.000). Conclusion: In this study, there was a statistically significant difference in vitamin D level between uncontrolled and controlled type 2 DM patients. Moreover, the correlation between vitamin D levels and HbA1c levels among the study sample was significantly inversed.
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