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Abstract
INCIDENCE AND TREND OF ANTIMICROBIAL SUSCEPTIBILITY AND RESISTANCE OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN DIABETIC FOOT ULCERS
Vinaya Ambore*, Harekrishna Vekariya, Chirag Kamat, Ravi Landge, Asmita Sen and Juveria Ansari
ABSTRACT
Introduction: The present study attempts to examine the microbial profile and antibiotic susceptibility of diabetic foot infections in patients admitted in surgical wards of a tertiary care centre for diabetic foot ulcers. Methodology: A prospective study was performed on 100 diabetic patients with foot ulcers admitted in surgical wards of a tertiary healthcare centre over a period of 24 months. Results: A total of 300 tissue samples were obtained from 100 patients during the study duration and evaluated for culture and antimicrobial susceptibility. Both Multimicrobial and unimicrobial infections are seen in culture. Gram positive cocci ‘Staphylococcus aureus’ was commonest isolate seen in culture. Other common isolates were coagulase negative staphylococcus(CoNS), acinetobacter, gram negative bacilli, anaerobes, mixed growth. In the wound culture sensitivity report, 31% cases were Staphylococcus aureus. 6% cases of which were sensitive to commonly used antibiotics called Methicillin sensitive staphylococcus aureus (MSSA) and the other 25% cases were Methicillin resistant staphylococcus aureus (MRSA). These were resistant to the commonly used antibiotics and sensitive only to higher antibiotics like meropenem, imipenem, tigecycline. Post higher antibiotics administration rendered the wound better and subsequent wound swab samples were culture negative and free of these superbugs MRSA.
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