WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Abstract

THE EFFECTS OF MULBERRY FRUITS (MORUS ALBA L.) EXTRACT ON ALLOXAN INDUCED DIABETIC RATS

Md. Mahmudul Hasan, Mst. Ismat Ara Begum and *Shahanaz Khatun

ABSTRACT

Objective: To investigate the protective role of Morus alba L. fruits against alloxan induced diabetic rats. Methods: Swiss albino rats were divided into five groups. The first group was used as non-treated control group, the second group was used as diabetic treated control group, the third group was diabetic treated mice plus methanolic extract of Morus alba L. fruits (200mg/kg body weight per day), the fourth group was diabetic treated mice plus ethanolic extract of Morus alba L. fruits (200mg/kg body weight per day) and the fifth group was diabetic treated mice plus glibenclamide. Serum indices related to diabetic, cardiac, renal and liver functions were determined to investigate the protective effect of Morus alba L. fruits on alloxan induced diabetic rats. Results: It revealed that the Morus alba L. fruits extract suplementation abrogated the alloxan induced elevation of glucose, total cholesterol, triglycerides, low density lipoprotein, urea, SGPT and SGOT. Morus alba L. fruits prevented the alloxan induced perturbation of serum high density lipoprotein cholesterol. Conclusions: The present study reported that the Morus alba L. fruits may be very useful for the improvement of the complications of alloxan induced diabetes.

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