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Best Article of current issue
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AN OBSERVATIONAL PROSPECTIVE STUDY ON EVALUATION OF PRESCRIPTION PATTERNS OF ANTIHYPERTENSIVE AGENTS IN TYPE 2 DIABETES MELLITUS ASSOCIATED WITH OR WITHOUT COMORBIDITIES
*Mudavath Santosh Nayak, Pilli Aishwarya, B. Vineeth Kumar and J. Jaya Lakshmi
Background: According to International Diabetes Federation- Diabetes Atlas 10th edition (2021) number of people with diabetes mellitus in south Asia are currently around 90 million and was predicted to 151.5 million by 2045. Aim: The main intention of the study is to evaluate the prescription patterns of antihypertensive in diabetes mellitus 2 connected with or without other disease and compute the blood pressure control and analyses the use of preferred antihypertensive therapy according to the JNC 8 guidelines. Materials and Methods: About 250 patients receiving antihypertensive and meeting the exclusion and inclusion criteria are assessed by observational study for 6 months. Data was collected in specially designed data collection form containing patient demographic details, past medication history, associated comorbidities. And the collected result was finally assessed with a statistical tool chi- square test by comparing the BP assessment in patients with anti- hypertensive prescriptions based on JNC8 guidelines. Results: Among 250 patients 150(62%) were treated with monotherapy and 92(38%) patients were prescribed with combination therapy, among 62% of patients using monotherapy 45% were on angiotensin receptor blocker, 28% were on beta blocker, 21% were on calcium channel blockers and 32% of patients were prescribed with two drug combination therapy other 6% of subjects are prescribed with more than 2 drug combination. Among the whole collected data 80% of population were treated effectively for their blood pressure management and Majority of the prescriptions were according to guidelines. Conclusion: 80% of population have effectively treated with antihypertensive therapy and majority of the prescriptions followed the guidelines although 20% of the population's blood pressure was not in control.[Full Text Article]