WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

EFFECTS OF AUTOLOGOUS PLATELET-RICH PLASMA ON RECEPTIVITY, IMPLANTATION AND PREGNANCY IN THIN ENDOMETRIUM, WITHOUT FETAL TRANSMIT

Dr. Latifa Baiazid*, Prof. Dr. Hasan Saleh and Prof. Dr. Thawra Naiseh

ABSTRACT

Background: Thin endometrium (TE) is a major challenge in infertility medicine and despite several methods that have been described for management, there is little consensus on the most effective one. Objective: The purpose of this study was conducted to evaluate the effectiveness of platelet-rich plasma (PRP) in improvement of receptivity, implantation, and, pregnancy rate in thin endometrium(TE) implantation that favoring the crosstalk between the embryo and the uterus improving the embryo-maternal dialogue. Study design: The study was prospective trial which condcted in department of obstetrics and gynecology, Tishreen University Hospital, Lattakia, Syria approved by the ethics committee of Tishreen University, and all participants signed an informed written consent. Results: 27 patients 5 patients had chemical pregnancies with 3 ongoing pregnancies, only 2 miscarricage, and 3 live birth. PRP application day was relevant with a significant probability of achieving pregnancy when the first PRP infusion was carried out at 10th day, and the second one at 12th day of the menstrual cycle. Conclusions: According to this study, it seems that Intrauterine autologous platelet- rich plasma (PRP) infusion is a safe, easily accessible, effective, and inexpensive therapy that could collaborate in fertility treatments, which improve thin endometrium by optimizing the receptivity, implantation and outcome in TE patients.

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