WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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ISSN 2457-0400

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Indexing

Abstract

MYOINVASIVE PATTERNS OF ENDOMETROID ENDOMETRIAL CARCINOMA & ITS PATHOLOGIC SIGNIFICANT

*Oula Kadhim Rasheed MBChB, Dr. Nazar Abdul Hassan Alwakeel and Musaddaq Mohammed abood

ABSTRACT

Introduction: Total abdominal hysterectomy with bilateral salpingo-oophorectomy is still the gold standard for treating endometrioid endometrial cancer, however lymphadenectomy (pelvic and/or para-aortic, systematic or selective) is debatable. This research aims to ascertain whether or not the MELF pattern of myometrial invasion is linked to an uptick in the occurrence of lymph node metastasis and, as a result, could be considered as an additional risk factor for endometrioid endometrial carcinomas that have progressed to stage D. Method: Cross sectional study of 68 females with endometrial carcinoma, the data collected from teaching laboratory in medical city, from 2020 to 2022. All cases take age of them and percentage of Myo invasion, lymph vascular involvement, lymph node metastasis, LUS invasion, cervical invasion and grades of tumor also we study the pattern of invasion. Results: [58.82%] of patients diagnosed as diffuse pattern of invasion, [22.06%] of patients diagnosed as MELF and [19.12%] of them diagnosed as pushing. There is significant association between Pattern of invasion and LVI, Lymph Node Metastasis, LUS invasion and grade of tumor. Conclusion: Most pattern of invasive of endometrium carcinoma is diffuse pattern, MELF Pattern of invasion are present with lymph node involvement, positive Lymph Node Metastasis, positive LUS invasion. Most of diffuse and MELF Pattern of invasion are on grade II.

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