WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

Impact Factor  :  6.711

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • .

    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • WJAHR: New Impact Factor

    WJAHR Impact Factor has been Increased to 6.711 for Year 2024.

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR March 2023 Issue has been Published, Kindly check it on https://www.wjahr.com/home/current_issues

  • WJAHR: MARCH ISSUE PUBLISHED

    March 2024 Issue has been successfully launched on 1 March 2024.

Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

Download Article : Click here

Indexing

Abstract

CONVENTIONAL PHOTOTHERAPY FOR HYPERBILIRUBINEMIA AND ITS RELATIONSHIP WITH THROMBOCYTOPENIA IN NEONATES

Arwa Youssef *, Abdul Moneim Ghanem and Hala Yanni

ABSTRACT

Background: Thrombocytopenia as a side effect of phototherapy has not been mentioned in standard literature but was described briefly as isolated case reports after the phototherapy. Though there are few studies on effect of phototherapy on platelet count with conflicting results. Aim and Objective: This study was done to determine the relationship between thrombocytopenia and its severity in neonates with uncomplicated indirect hyperbilirubinemia receiving conventional phototherapy. Materials and Methods: This prospective observational study was carried out over a period of one year (1st September 2020 to 1st September 2021) on 56 neonates admitted with idiopathic unconjugated hyperbilirubinemia needing phototherapy through consecutive enrolment. Serum bilirubin (total, conjugated and unconjugated) and platelet count were done before initiation, twenty-four hours after phototherapy and just after completion of phototherapy. Appropriate statistical tests were used to make statistical comparisons with a p-value of < 0.05 taken as significant. Results: Among 56 neonates, 30(53.6%) were males and 26(46.4%) were females; 23(41.1%) were preterm neonates and 33(58.9%) were term neonates. Mean birth weight was (2493.3 ± 420.2) g. Mean gestational age was (36.94 ±1.6) weeks. The mean duration of phototherapy required was (32.87±5.7) hours. Mean platelet count before initiation, 24 hours after phototherapy and just after completion of phototherapy were (286.25 ±46.3) ×10?/L, (249.82±78.7) ×10?/L and (233.96±94.1) ×10?/L respectively. Decrease in platelet count 24 hours after phototherapy and just after completion of phototherapy was statistically significant (P-value=0.0001). Thrombocytopenia was seen in 14 neonates (25%) and type of severity was mild and moderate in 10(71.4%) and 4(28.6%) respectively but none developed sever thrombocytopenia. None having thrombocytopenia manifested with clinical bleed. Fall in platelet count was found to have a positive association with increased duration of phototherapy and in preterm neonates (P-value0.05) between reduction in platelet count with gender and birth weight. Conclusion: we found that there was a significant association between phototherapy and thrombocytopenia in hyperbilirubinimic neonates but the thrombocytopenia was mostly mild and transient, and clinically insignificant. There was significant association between decrease of platelet count with duration of phototherapy and preterm neonates.

[Full Text Article] [Download Certificate]