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Abstract
MODIC CHANGES AND THEIR ASSOCIATION WITH INTERVERTEBRAL DISC CHANGES SEEING BY MRI IN PATIENTS WITH LOW BACK PAIN
Hussein Harfoush*, Fawaz Baddour and Mohammed Abdulrahman
ABSTRACT
Introduction: The characterization of Modic changes visible by magnetic resonance imaging(MRI) in the lumbar spine in patients with low back pain, and the definition of their patterns and distribution according to gender, age, and lumbar motion segment, and the proportions of their association with degeneration of the adjacent intervertebral discs and the morphological changes in them, is very important in order to reach a more accurate diagnosis, which may change the direction of management and treatment plan for these patients. The Aim of the Research: Characterization of Modic changes visible by MRI in the lumbar spine in patients with low back pain, and investigating the relationship between them and other variables in the adjacent cartilaginous disc (disc degeneration, intervertebral disc shape), and determining the proportions of the distribution of these changes according to gender, age, lumbar motion segment, and the most common Pattern in patients with low back pain. Materials and Methods: A total of 156 patients were enrolled. Gender, age, lumbar motion segment, grade of paravertebral disc degeneration, and intervertebral disc shape, respectively, were documented. Modic changes and their relationship with the mentioned variables were studied using a descriptive cross sectional study. Results: A total of 18 patients had type I changes, 124 patients had type II changes, and 14 patients had type III changes. In total, 213 affected lumbar motion segments were seen, L1/L2 (5 segments), L2/L3 (17 segments), L3/L4 (27 segments), L4/L5 (48 segments) and L5/S1 (116 segments). Type I changes were mainly seen under the age of 50. The descriptive cross-sectional study showed that gender, age, lumbar motion segment, paravertebral disc degeneration, and intervertebral disc shape were associated with different patterns of Modic changes. Conclusion: Type II changes are the most common, followed by type I changes. Modic changes occur mostly in L4/L5 and L5/S1; It was found that the age of youth, males, and disc protrusion were associated with the changes of the first type.
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