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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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THE POTENTIAL IMPACT OF PHARMACOGENETICS ON PERSONALIZED MEDICINE AND MEDICATION COMPLIANCE: A REVIEW
M. D. M. Fernando*, N. H. K. S. Senathilake and B. G. D. N. K. De Silva
The expansion of gene cloning, DNA genotyping and sequencing have greatly influenced the enlargement of the applications of Pharmacogenetics in drug discovery and development. It is used to unveil inherited genetic alterations in different drug metabolic pathways leading to varied pathological and therapeutic response. Personalized medicine is a medical model that tailor therapy with the best response and maximum safety limits to secure better patient care. It is tailored to the different characteristics of individual patients that is relied on person's distinctive genetic and molecular profile making them vulnerable to different diseases. However, therapeutic response is largely dependent on medication compliance that generally describes the extent to which patients correctly take medications by strictly obeying to the medical advises. In addition, it is based on the factors such as getting prescriptions filled, remembering to take medication on time, correct use of home medical devises, self-directed exercises, self-care, therapy sessions, and comprehending the directions.[Full Text Article]