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World Journal of Advance Healthcare Research (WJAHR) is giving Best Article Award in every Issue for Best Article and Issue Certificate of Appreciation to the Authors to promote research activity of scholar.
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Abstract
ROTH SPOTS IN THE DIAGNOSIS OF ACUTE MYELOID LEUKEMIA IN YOUNG ADULTS
Thiago Sande Miguel, Bruna Sande Miguel, Vinicius Sande Miguel, Rafaella Pereira Neiva, Amanda Dinalli Francisco, Eduardo de França Damasceno, Marcelo Jarczun Kac, Helena Parente Solari and Daniel Almeida da Costa*
ABSTRACT
Acute myeloid leukemia (AML) is a malignant disease of stem cell precursors of the myeloid lineage. AML remains a rare malignancy, accounting for only 1.2% of all new cancer diagnoses in the United States each year. AML is most common in adults with an incidence of more than 20,000 cases per year in the country. It is a highly heterogeneous disease with cases being stratified into risk groups based on their cytogenetic profile. When there is ocular involvement, the retina and choroid are the most commonly affected areas, with several clinical manifestations. Despite great advances in understanding its pathophysiology, treatment options have not significantly changed in the last three decades. Allogeneic hematopoietic stem cell transplantation remains the best chance for a cure.
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