WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

Abstract

CLINICOPATHOLOGICAL ASSESSMENT OF THYROID MALIGNANCIES IN A SAMPLE OF PATIENTS IN BAGHDAD DISCRETE

*Zainab Khaldoun Jabur M.B.Ch.B. and 2Ban Jumaah Qasim PhD

ABSTRACT

Background: Thyroid cancer is the most common malignancy of endocrine system, increasing incidence is mainly due to early detection of small cancers; it occurs at any age; it is about (3-4) times higher among women than men, in Iraq represents the 2nd cancer in women. Aim of study: To count the frequency of types of thyroid malignancies in a sample of Iraqi patients in Baghdad discrete, and to assess the clinicopathological parameters in the studied cases. Methods: Retrospective and prospective study including analysis of100randomly selected patients with thyroid malignancies collected from Teaching Laboratories of Al-Emamain Al-Kadhmain Medical City (AS) and Baghdad Medical City from January 2018 to January2019; collected samples were formalin fixed paraffin embedded blocks and hematoxylin and eosine stained slides; as well as clinicopathological data from patients' case sheet. Results: Most patients at age (30-39), female to male ratio was 6.69:1. Ninty one percent of patient had goiter with significant association with papillary carcinoma, 28% of cases had lymphadenopathy with significant association with medullary carcinoma, 48%of cases had tumor size (1-3) cm3 and 57%presented in stage T1 with significant association with papillary carcinoma. Conclusion: Most common type of thyroid malignancy in this study was papillary carcinoma then follicular and medullary carcinoma; borderline thyroid tumor represents 22% of cases, correlation between history, physical examination, laboratory examination, ultrasound (U/S) finding and histopathological features are essential for diagnosis.

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