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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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A REVIEW ON PYRIMIDINE HETEROCYCLES
Kiranbir Kaur*, Sharanjit Kaur, Prabhsimran Singh and Sandeep Rahar
Pyrimidine is a heterocyclic aromatic organic compound containing two nitrogen atoms at positions 1 and 3 of the six- member ring shows wide range of biological activities. Literature indicates that compounds having pyrimidine nucleus have wide range of therapeutic uses. Pyrimidine have been reported to show array of activities like antiinflammatory, antibacterial, anticancer, antiviral, antiHIV, antimalarial, antihypertensive, sedatives and hypnotics, anticonvulsant and antihistaminic. Pyrimidine are among the most frequently encountered scaffolds in drugs and pharmaceutically relevant substances. The nitrogen heterocycles are an attractive source of compounds for the identification of new biological probes. The present reviews attempted to gather the various biological activities of pyrimidine derivatives. This assemblage reveals the emergence of this scaffold in the medicinal chemistry with force on the discovery of nitrogen containing heterocyclic candidates.[Full Text Article]