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Abstract
PREDICTIVE VALUE OF NEUTROPHIL TO LYMPHOCYTE RATIO AND PLATELET TO LYMPHOCYTE RATIO IN DIABETIC PERIPHERAL NEUROPATHY PATIENTS TYPE 2 DIABETES
Maha Jdeed*, Arije Boubou and Tagrid Kaddar
ABSTRACT
Background: Diabetic peripheral neuropathy (DPN) is one of the most common chronic complications of diabetes mellitus (DM). Further development of DPN can lead to diabetic foot, ulcers, amputation, seriously affecting patient life quality. Therefore, searching for a reliable indicator of DPN early diagnosis is of most significance. Neutrophil to lymphocyte ratio (NLR) and platelet to lymphocyte (PLR) have a close relationship with cancer, cardiovascular diseases, and diabetic microvascular concurrency diseases. We aimed to investigate the relation between NLR, PLR and DPN. Methods: A total of 129 newly diagnosed type 2 diabetes mellitus (T2DM) patients were recruited, including 43 patients without complication (DM group) as well as 86 patients complicated with DPN (DPN group). Student t test, Mann- Whiney U test, or x2 test was applied to the data of the 2 groups. Results: NLR and PLR values were remarkably higher in DPN group compared to those of DM group (2,43±1,05 vs 1,31±0,19, P?0,001), (141.26± 63.36 vs 104.93± 44.89, p
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