WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Frastiqa Fahrany*, Dedi Kurniawan**, Lailatul Kodriyah** and Galuh Kumalasari**

ABSTRACT

Contaminated wound incidents is still high and it can be an infected wound. People usually treat contaminated wound with antiseptic agent such as povidone iodine 10% but it can cause skin colour change and irritation. Aloe vera extract has active compounds suspected to act as antiseptic such as saponin and phenol. This experiment was conducted to know the ability of Aloe vera extract as antiseptic against bacteria reduction compared with povidone iodine 10% on contaminated wound. Twenty four female wistar rats were randomly devided into six groups. A 2,5 cm incision wound was made on each sample’s back that opened for three hours. The treatment groups were treated with 50%, 60%, 70%, 80%, and 90% Aloe vera extract, control group was treated with Povidone iodine 10%. Data obtained were analyze by one-way ANOVA. The result showed there were differences in concentration changes of Aloe vera extract and and povidone iodine 10% to the bacteria reduction (p=0,029). Aloe vera extract 90% showed the highest bacteria reduction but wasn’t significantly different with Povidone iodine 10%. Correlation test showed the relationship between the concentration of extract with bacteria reduction (R=0,646; p=0,001). Based on the result, it can be concluded that Aloe vera extract 90% has the same effectiveness with Povidone iodine 10% in reducing bacterial on contaminated wound.

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