WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Ali Ibrahim Mohammed*, Najmaddin Salih Khoshnaw, Samer Ibrahim Mohammed, Asmaa Mohammed Thanun and Zhwan Niazi Baker

ABSTRACT

The physiological changes in pregnancy that help in the raising and survival of the fetus are reflected in the hematological parameters changes and the abnormal hematological profile affects pregnancy and its outcome. Our study aimed to evaluate the values of hematological parameters at different trimesters of pregnancy. Patients and methods: A cross-sectional survey included 204 healthy pregnant women and 150 normal non-pregnant women as control. Healthy pregnant women of all gestational ages who attended the Sulaimania Obstetrics Hospital, for over 9 months from October 2019 to August 2020. Five milliliters of venous blood samples were taken from both the pregnant woman and control group, 2.5 ml in K3—EDTA tubes for the hematological examinations and the rest of 2.5 ml was placed in a gel tube for CRP. The analysis of hematological indices was done using the automated hematological analyzer. Results: Hb, Hct, MCH, MCV, lymphocytes, RBCs, and platelets count are decreased significantly while the WBCs count and neutrophils are increased in pregnant women in comparison with control. A progressive decline in Hb, hematocrit, and lymphocytes from the first to the third trimester, on the contrary, there is a progressive increase in granulocytes (absolute and percent) and RDW% with the advance of pregnancy, though there was no statistically significant difference in total WBC count among different gestational age. Conclusion: The hematological parameters are significantly changed at different trimesters of pregnancy. Anemia in pregnancy is the most common hematological problem, followed by thrombocytopenia.

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