WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

World Journal of Advance Healthcare Research (WJAHR) has indexed with various reputed international bodies like : Google Scholar , Index Copernicus , SOCOLAR, China , Research Bible, Fuchu, Tokyo. JAPAN , Cosmos Impact Factor , Scientific Indexing Services (SIS) , UDLedge Science Citation Index , International Impact Factor Services , International Society for Research Activity (ISRA) Journal Impact Factor (JIF) , IFSIJ Measure of Journal Quality , Scientific Journal Impact Factor (SJIF) , International Scientific Indexing, UAE (ISI) (Under Process) , International Impact Factor Services (IIFS) , Web of Science Group (Under Process) , Directory of Research Journals Indexing , Scholar Article Journal Index (SAJI) , International Scientific Indexing ( ISI ) , Academia , Scope Database , 

ISSN 2457-0400

Impact Factor  :  6.711

News & Updation

  • Article Invited for Publication

    Dear Researcher, Article Invited for Publication  in WJAHR coming Issue.

  • Journal web site support Internet Explorer, Google Chrome, Mozilla Firefox, Opera, Saffari for easy download of article without any trouble.

    .

  • 6th International Conference on Human and Soci

    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

  • New Issue Published

    Its Our pleasure to inform you that, WJAHR April 2024 Issue has been Published, Kindly check it on https://www.wjahr.com/home/current_issues

  • .

    6th INTERNATIONAL CONFERENCE ON EDUCATIONAL TECHNOLOGY AND CURRICULUM STUDIES(ICETC2019) 

     

    Venue: FCT Education Resource Center, Abuja-Nigeria

    September 22-24, 2019

  • WJAHR: New Impact Factor

    WJAHR Impact Factor has been Increased to 6.711 for Year 2024.

  • WJAHR: APRIL ISSUE PUBLISHED

    APRIL 2024 Issue has been successfully launched on 1 APRIL 2024.

Best Paper Awards

World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.

Best Article of current issue

Download Article : Click here

Indexing

  Indexing

  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

HYPOGLYCEMIC EFFECT OF ‘PORANG’ FLOUR (Amorphophallusmuellery Blume) ON HYPERGLYCEMIC RATS AND IN SILICO PHARMACODYNAMICS ANALYSIS

Novita Dewi*, Karyono Mintaroem, Moch Muljohadi Ali, Hidayat Suyuti, Hani Susianti

ABSTRACT

Background: An acute hyperglycemia is a life-threatening emergency, occurring in patients with plasma glucose more than 600 mg/dL. Hyperglycemia could be managed by lowering blood plasma glucose.Porang bulb (AmorphophallusmuelleriBlume) is expected to have a hypoglycemic effect on hyperglycemic rats, and there is no in-silico mechanism explaining the process. This study aimed to investigate the hypoglycemic effect of Porang flour (AmorphophallusmuelleriBlume) in hyperglycemic rats and its in-silico pharmacodynamics analysis. Methods: The study was performed on25 hyperglycemic rats with the pre-post test only control group design. Rats was divided equally in five groups, namely normal group (K), hyperglycemic group (K+), Porang flour treatment group with dose 100 mg/kgBW (P1), Porang flour treatment group with dose 200 mg/kgBW (P2), and Porang flour treatment group with dose 400 mg/kgBW (P3).Induction of hyperglycemia was performed with 60% high fructose diet and intraperitoneal STZ injection with dose 25 mg and 30 mg. We measured pre test blood glucose. The insilico instruments used werepubchem and molinspiration, icd lab, string and stitch, pymol, and pyryx.The data were analyzed usingt test (p

[Full Text Article] [Download Certificate]