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Abstract
ASSOCIATION BETWEEN AGE AND GLEASON SCORE IN PROSTATIC ADENOCARCINOMA
*Umniyah Nafea Ahmed and Dr. Nadia H. Ibraheem
ABSTRACT
Introduction: Carcinoma of prostate (PCa) is the most public non-cutaneous tumor for males. It is probable that till the year 2030 the incidence of PCa will upsurge by 55%, 71% of males with the illness will be 65 years’ age. The aim of the study is to assess the impact of age at the time of surgery on the prognostic stratification using Gleason score in prostatic adenocarcinoma. Method: cross sectional study of 70 FFPE blocks/prostatic adenocarcinoma collected from surgical specialties hospital, medical city, Baghdad from January 2019 to December 2021, age of patients 50-90 years, Specimen-surgical specimen, Histopathology assessment-different Gleason score used as a template to assess architectural features based on reports from different consultants. Results: mean age of them are (68.5 ± 7.5) years old, 35 (50%) of patients at age group ?70 years, 30 (42.9%) of patients at age group 60-69 years. 18 (25.71%) of patients have Gleason score 3+4, 15 (21.43%) of patients have Gleason score 4+3, 12 (17.14%) of patients have Gleason score 3+3, 4+4. There is no significant relationship between age groups and Gleason score. Conclusion: old age highly associate with risk of prostatic carcinoma and increase Gleason score, so must do early screening for all elderly individuals for prostatic cancer. Most prevalence of prostatic carcinoma occurs in male with age group more than 60 years old, and most Gleason score 3+ 4.
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