WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Sahar Tareq Abduljabaar and Sazan Abdulwahab Mirza

ABSTRACT

Background: The aim of endoscopy of the upper digestive tract as a routine diagnostic procedure has increased the number of gastric and duodenal biopsy specimens. In gastric biopsy to evaluate inflammatory processes including Helicobacter pylori related gastritis and alterations of the mucosa secondary to mucosal injury, generally referred to as reactive gastropathy. The aim of study is to histopathological evaluation of gastric and duodenal biopsy in cases of patient presented with dyspepsia and to study the correlation between some histopathological measures and causes of dyspepsia (age, sex, diagnosis). Method: This is a retrospective cross-sectional study, included a total of 150 cases obtained from gastric and duodenal biopsy, conducted from archived material (Gastroenterology and hepatology teaching hospital). covering the period from (June 2019 to November 2021). It included Endoscopic (Gastric and Duodenal biopsies), tissue paraffin block. Each block was sectioned into one slide and stained with H&E stain. Results: No statistically significant association was found between sociodemographic characteristics (age and gender) and either gastric or duodenal biopsies. A statistically significant association was found between both gastric and duodenal biopsies. Conclusion: No association was found between gastric histopathological findings and either age or gender. No association was found between duodenal histopathological findings and either age or gender. A significant association was found between gastric and duodenal histopathological findings, which when taken in consideration with the high prevalence of H. pylori infection, can explain the very high percentage of abnormal duodenal biopsies.