WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

*Dr. Mohammad Esmael Khaleel, Dr. Jumana Khairuddin Abd-alqader and Dr. Atallah Khaleel Ibrahim

ABSTRACT

Background: Gout is one of the common inflammatory arthritis, that occurs due to deposition of mono sodium urate crystals in the joint or soft tissue. The prevalence of gout is increasing in the last years globally, although it is a preventable and a controllable disease if well managed. There are many risk factors that cause it could be modified like; life style and physical activity, diets, comorbidities and certain drugs intake while age and gender with genetic factor and family history are non-modifiable one. Objective: To study risk factors of gout in Mosul city. Methodology: A case-control study design was carried out in the main hospitals of Mosul city, Iraq. A total of (50) cases and (100) controls were collected. The period of collection of both cases and controls was from January 2021 to June 2021. Results: Gout is mainly a male disorder with p value (0.011) and there is marked increase in the number of female affected with advancing age, consumption of purine rich foods of animal origin are significant risk factor in Mosul population with p value (0.000) and alcohol intake p value (0.016), while consumption of diet rich in vegetables, fruits, and low fat dairy products are protective with p value (0.000) for each. Lack of physical activity and diabetes and cardiovascular diseases are also strong risk factors with p value (0.014)(0.019)(0.021) respectively, in addition to diuretics use p value (0.027), there is also a significant result for positive family history p value (0.001) and most of them from father side. Apart from risk factors some observation regarding the cases documented during the study in which; the first metatarsal joint is the most common site affected, and the first gout attack mostly diagnosed during Spring mainly at April &May, while recurrent flare aggravated in Winter season and many patients documented fruits and vegetables with drinking plenty of water relieve their symptoms. Conclusion: Being male and having a positive family history increase risk for getting gout, in addition to certain chronic illnesses like diabetes and cardiovascular diseases, with diuretics use and alcohol intake with lack of physical activity all of them are marked risk factors of gout in Mosul city.