WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

Suad M. Ghazi*

ABSTRACT

Background: One of the common disorders that affect females of reproductive age is the Poly-Cystic Ovarian Syndrome (PCOS). Thyroid dysfunction is also more prevalent in this age group. This study aimed to evaluate the prevalence of thyroid dysfunction in women with PCOS in comparison with control and to investigate the association between hypothyroidism and PCOS in women of ovulatory age. Patients and Methods: Eighty female subjects of fertility age were selected and divided into two equal groups. The first 40 subjects are healthy females as a control group. The second 40 group are patients with PCOS. The PCOS women were diagnosed by Rotterdam criteria and performed thyroid tests, sex hormones and lipid profile tests. Results: The results show that PCOS women with hypothyroidism are tending have a high body mass index (BMI). Forty-five percent of PCOS patients had hypothyroidism which was investigated in TSH and T4 tests by 35% and 10%, respectively. A high level of testosterone was found in females with PCOS. The cholesterol shows a significant correlation with the alteration in Thyroid Stimulating Hormone (TSH). Conclusion: There is a correlation between thyroid dysfunction especially hypothyroidism with the polycystic ovarian syndrome because both of them lead in features to metabolic syndrome and there is a high prevalence of hypothyroidism in women with PCOS.