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World Journal of Advance Healthcare Research (WJAHR)Honored the authors with best paper award, monthly based on the innovation of research work. Best paper will be selected by our expert panel.
Best Article of current issue
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CENTRAL NERVOUS SYSTEM TUMORS IN IRAQI PATIENTS WITH CLINICOPATHOLOGICAL CORRELATION
*Fatimah Ahmed Abdulridha and Dr. Wissam A. Lateef
Introduction: Neoplasm of central nervous system considered the main problems in health system, it lead to many neurological deficits and related to opposed prognosis so it need to know the prevalence of illness to early treatment and prevention. The aim of this study was to investigate the clinicopathological correlation for brain glioma, it’s relation to age, and gender, site, size and grade in patients underwent incisional and excisional brain biopsies. Method: The cross sectional study, pathology reports of a 200 patients underwent surgery for removing brain masses and sent for pathology laboratory were collected from the archive of the teaching laboratories of Ghazi Al Hariri hospital in Baghdad/Iraq in the period from January 2019 to October 2021. The histopathology reports were including age and gender of the patients, site of the surgical procedure, size of the biopsy. All the biopsied materials were fixed in 10% formalin solution, undergo routine tissue processes, were embedded into paraffin blocks and stained with hematoxylin and eosin stains. Results: mean age (34.1 ± 20) years old, mean tumor size (3.5 ± 2.4). 38 (19%) of patients at age group 21-30 years, 35 (17.5%) of patients at age group 41-50 years old, 117 (58.5%) of patients are males and 83 (41.5%) of patients are females, 117 (58.5%) of patients with size of tumor <3mm, 140 (70%) of patients the tumor location in Cerebral hemisphere and 29 (14.5%) at posterior fossa. 83 (41.5%) of patients at grade 4 and 55 (27.5%) of patients at grade 2. There is significant association between age > 60 years, male gender, size ? 3 mm site and grade 4 with histopathological diagnosis. Conclusion: There is high clinicopathological correlation for brain glioma, Glioblastoma Multiforme associate with age more than 60 years, male gender, cerebral hemisphere and thalamic site, tumor size ?3mm, and grade 4.[Full Text Article]