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Abstract
CORONARY ARTERY DISEASE IN DIABETIC WOMEN AND MEN –PROSPECTIVE STUDY AT TERTIARY CARE HOSPITAL FROM NORTH INDIA
Premshanker Singh*, Jyoti Verma, Himanshu Sharma, Granth Kumar and Vidya Sagar
ABSTRACT
Previous analyses have shown that women with diabetes are at substantially increased risk of Coronary Heart Disease (CHD) compared with men. Several larger studies have been published on the sex-specific associations between diabetic women and men for incident CHD. We performed this study to provide the most reliable evidence of any sex difference in the effect of diabetes on subsequent risk of CHD This prospective population-based study was carried out at UP University of Medical Sciences, India wef 07 Apr 2006 t0 07 Apr 2017(11 yrs) years The diabetes have more than a 40% greater risk of incident CHD in women as compared with men. Data from Single center, including 858,5 individuals and 28,2 incident CHD events, were included. The RR for incident CHD associated with diabetes compared with no diabetes was 2.82 (95% CI 2.35, 3.38) in women and 2.16 (95% CI 1.82, 2.56) in men. The multiple-adjusted RRR for incident CHD was 44% greater in women with diabetes than in men with diabetes (RRR 1.44 [95% CI 1.27, 1.63]) with no significant heterogeneity between studies Coronary artery disease (CAD) is the leading cause of cardiovascular mortality worldwide Despite a recent decline in developed countries, both CAD mortality and the prevalence of CAD risk factors continue to rise rapidly in developing countries.
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