WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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Indexing

Abstract

CIGARETTE SMOKING AND METABOLIC SYNDROME COMPONENTS: A PROSPECTIVE STUDY FROM NORTH INDIA

Premshanker Singh*, Mridu Singh, Vikram Singh and P. K. Singh

ABSTRACT

Adverse impact of tobacco products on health has been well established for more than 50 years[1,2] Consumption of tobacco is a risk factor for six of the world's eight leading causes of death[3,4] Projected to kill around 1 billion people in this century, it remains the commonest preventable and modifiable contributor to morbidity and mortality globally. Apart from the direct tobacco smoke, exposure to second-hand tobacco smoke (SHS) causes illness, disability, and death from a wide range of diseases[3,5] In fact, it contributes to about 1% of the total global disease burden[1,2,3,4] A growing body of evidence suggests that cigarette smoking can cause the onset of metabolic syndrome prior to cardiovascular diseases. Therefore, the objective of this study was to evaluate the relationship between smoking habit and metabolic syndrome(METs) components in an adult population from Lucknow, India Prevalence Study is a descriptive, cross-sectional study with random and multi-stage sampling. In this sub-study, 1106 adults from both genders were selected. On the basis of their medical background, they were classified as smokers, non-smokers and former smokers. Metabolic syndrome was defined according to IDF ATP-3 Criteria, using population-specific abdominal circumference cut-off points. The association between risk factors was evaluated using a logistic regression model In the studied population, 14.8% were smokers, 15.4% were former smokers. In the multivariate analysis, the presence of metabolic syndrome (smokers: OR, 1.54; 95% CI, 1.11–2.14; p=0.010) and its components were related to cigarette smoking, with the exception of hyperglycemia. High blood pressure was inversely associated with current smoking status (smokers: OR, 0.70 (0.51–0.95); p=0.025). Cigarette smoking represents a related factor with metabolic syndrome, being associated with low high-density lipoprotein-cholesterol, increased abdominal circumference, Low plasma fasting sugar, elevated Blood Pressure and high triacylglyceride levels. Former smokers did not present a greater risk for developing this metabolic disease when compared to non-smokers. The effect of avoiding this habit should be evaluated in future studies in our population.

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