WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
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Abstract

BIOLOGICAL EVALUATION OF IN-VIVO ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF PAEDERIA FOETIDA ROOT EXTRACT

Kurra Sruthi* and Kodi Gnaneshwari

ABSTRACT

The ethanolic root extract of Paederia foetida was evaluated for its analgesic and anti-inflammatory activities using different models of Pain and Inflammation. The analgesic activity of Paederia foetida was carried out using tail-flick, eddy’s hot plate and acetic acid induced writhing response in mice. Further in-vivo anti-inflammatory study was performed using carrageenan- induced rat paw edema in rats. The ethanolic root extract of Paederia foetida at a dose level of 100 and 200 mg/kg were tested for its therapeutic potential. The results were found to be encouraging in all animal models and the results were tabulated in detailed. Paederia foetida root extract possess significant analgesic and anti-inflammatory activities against various models of inflammation and pain.

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