WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals

An Official Publication of Society for Advance Healthcare Research (Reg. No. : 01/01/01/31674/16)

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  • Google Scholar
  • Index Copernicus
  • SOCOLAR, China
  • Research Bible, Fuchu, Tokyo. JAPAN
  • Cosmos Impact Factor
  • Scientific Indexing Services (SIS)
  • UDLedge Science Citation Index
  • International Impact Factor Services
  • International Society for Research Activity (ISRA) Journal Impact Factor (JIF)
  • IFSIJ Measure of Journal Quality
  • Scientific Journal Impact Factor (SJIF)
  • International Scientific Indexing, UAE (ISI) (Under Process)
  • International Impact Factor Services (IIFS)
  • Web of Science Group (Under Process)
  • Directory of Research Journals Indexing
  • Scholar Article Journal Index (SAJI)
  • International Scientific Indexing ( ISI )
  • Academia
  • Scope Database

Abstract

NOVEL NANOGEL APPLICATIONS: A REVIEW

Rashad M. Kaoud*, Eman J. Heikal and Lina M. Jaafar

ABSTRACT

The term Nanogels (NGs) refers to a hydrogel nanoparticle with a network of cross-linked hydrophilic polymers. NGs are nanoparticles made up of cross-linked polymer that expand in a suitable solvent. For polynucleotide delivery, cross-linked networks of a poly ion, a nonionic polymer (cross-linked polyethyleneimine (PEI) and poly (ethylene glycol) (PEG). The creation of NGs systems that have capability to supply medicaments in a targetable, controlled, and sustained manner has been necessitated due to the sudden explosion in the field of nanotechnology. As clinical trials progress, it is now unavoidable to develop smart nano-systems that can be used for treatment due to the growing field of polymer sciences. The goal of this brief review is to provide comprehensive examples of novel NGs applications, drug loading techniques, and drug release mechanisms. Furthermore, the current state of NGs, the status of clinical trials and future prospects have been summarized.

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