WORLD JOURNAL OF ADVANCE
HEALTHCARE RESEARCH

( An ISO 9001:2015 Certified International Journal )

An International Peer Review Journal for Medical Science and Pharma Professionals
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ISSN 2457-0400

Impact Factor  :  5.464

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    Venue:FCT Education Resource Center, Abuja- Nigeria                                        September 22-24, 2019

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Indexing

Abstract

MICROORGANISMS RESISTANCE PATTERN AND ANTIBIOTIC PRESCRIPTIONS IN PATIENTS ADMITTED TO THE INTENSIVE CARE UNIT IN GHAZY AL HARIRI HOSPITAL

Laith G. Shareef*, Ayad Abbas Salman, Fadil Agla Bonyan, Mohammed A. Taher and
Ibrahim Mohammed Ameen

ABSTRACT

Resistance to antibiotics has emerged recently due to the misuse of antibiotics and is a threat to the health?care system, especially in developing countries like Iraq where there are no antimicrobial stewardship programs in most intensive care units (ICU). Our objective to investigate the antibiotic prescribing pattern in ICU, organisms, and its resistance pattern and its influences on the all-cause mortality as there is sparse data in Iraqi ICUs. This was an observational, cross-sectional study done in the ICU of Ghazi AL Hariri hospital, Medical City/Iraq. All patients getting admitted to ICU from both genders were included in the study. Samples taken for culture and sensitivity tests included blood, urine, tracheostomy tube, sputum, cerebrospinal fluid, central venous line, and bedsore swab. Patients followed until they stabilized or died. 43 patients satisfied the inclusion and exclusion criteria and were included in the study. The mean age of the study population was 50.72 years. The most common isolated pathogens were pseudomonas in sputum and blood samples, Acinetobacter in wounds and operation skin site infection, Klebsiella in central venous line, and bedsore swab, while Candida in the urine. Klebsiella was the most frequently isolated in overall culture results, it was most sensitive to imipenem, meropenem, and amikacin. Ceftriaxone was the most commonly used antibiotic as an empiric treatment followed by meropenem and amikacin. Most of the isolated pathogens (> 90%) had resistance to ceftriaxone. ICU-acquired Klebsiella, P. aeruginosa, and Acinetobacter predominate hospital-acquired infections.

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